Cal Poly Pomona

Physics Seminar

Friday, October 24, 2008

Multi-scale Modelling for Threshold Dependent Cellular Differentiation

Anna Cai

Department of Mathematics, University of California, Irvine

The maintenance of a stable stem cell population in the epidermis is important for the constant regeneration of the stratified epithelium. The population size is regulated by cell secreted diffusible extra-cellular signalling molecules as well as intra-cellular molecules. A mathematical model incorporating both levels of regulation is used to examine the balance between growth and differentiation for the stem cell population. The dynamics of the known differentiation regulator, c-Myc, and its effect on regulating a stable stem cell population is examined.

Refreshments at 4:00 PM. Seminar begins at 4:10 PM.
Building 8, Room 241
For further information, please call (909) 869-4014

Last modified on October 18, 2008
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