Junjun Liu

Junjun Liu

Ph.D., Professor, Department of Biological Sciences, College of Science

Email

Phone number

909.869.2505

Office location

Building 4, 1-414

Office hours

M | 2-3 PM

Education and Academic Training

B.S.,  Molecular Biology and Virology, Wuhan University, China

Ph.D.,  Molecular Biology and Biochemistry, The University of Melbourne, Australia

Postdoc,  Cell Biology, Howard Hughes Medical Institute (HHMI), USA

Research Interests

This lab studies the molecular mechanism underlying the regulation of metastasis. Currently, we focus on the role of epigenetic modification, specifically, the ubiquitination and deubiquitination of histone H2A, in regulating the migration and invasion of breast cancer cells. This project is supported by a fund from NIH.

 

Misaligned chromosomes in cells.mp4 

The video above shows our finding that if the activity of deubiquitinase USP16 is impaired, the chromosome alignment during mitosis is significantly affected, which may ultimately cause cancer.